Srilaxmi Kalavalapalli

Srilaxmi Kalavalapalli,

Medical Scientist IV; Manager, Endocrinology & Diabetes Research Laboratory

Department: MD-ENDOCRINOLOGY
Business Phone: (352) 273-8490

Publications

2023
Adipose Tissue Insulin Resistance Predicts the Severity of Liver Fibrosis in Patients With Type 2 Diabetes and NAFLD.
The Journal of clinical endocrinology and metabolism. 108(5):1192-1201 [DOI] 10.1210/clinem/dgac660. [PMID] 36378995.
2023
Pioglitazone discontinuation in patients with nonalcoholic steatohepatitis is associated with disease recurrence.
Diabetes, obesity & metabolism. 25(4):1112-1116 [DOI] 10.1111/dom.14936. [PMID] 36495442.
2022
Assessing strategies to target screening for advanced liver fibrosis among overweight and obese patients.
Metabolism and target organ damage. 2 [DOI] 10.20517/mtod.2022.08. [PMID] 36017449.
2021
Advanced Liver Fibrosis Is Common in Patients With Type 2 Diabetes Followed in the Outpatient Setting: The Need for Systematic Screening.
Diabetes care. 44(2):399-406 [DOI] 10.2337/dc20-1997. [PMID] 33355256.
2021
Intact Fasting Insulin Identifies Nonalcoholic Fatty Liver Disease in Patients Without Diabetes.
The Journal of clinical endocrinology and metabolism. 106(11):e4360-e4371 [DOI] 10.1210/clinem/dgab417. [PMID] 34190318.
2021
Severity of non-alcoholic steatohepatitis is not linked to testosterone concentration in patients with type 2 diabetes.
PloS one. 16(6) [DOI] 10.1371/journal.pone.0251449. [PMID] 34077443.
2020
Relationship between non-alcoholic fatty liver disease during pregnancy and abnormal glucose metabolism during and after pregnancy.
Journal of investigative medicine : the official publication of the American Federation for Clinical Research. 68(3):743-747 [DOI] 10.1136/jim-2019-001186. [PMID] 31852748.
2020
Targeting pheochromocytoma/paraganglioma with polyamine inhibitors.
Metabolism: clinical and experimental. 110 [DOI] 10.1016/j.metabol.2020.154297. [PMID] 32562798.
2019
Effect of canagliflozin treatment on hepatic triglyceride content and glucose metabolism in patients with type 2 diabetes.
Diabetes, obesity & metabolism. 21(4):812-821 [DOI] 10.1111/dom.13584. [PMID] 30447037.
2019
Impact of exenatide on mitochondrial lipid metabolism in mice with nonalcoholic steatohepatitis.
The Journal of endocrinology. 241(3):293-305 [DOI] 10.1530/JOE-19-0007. [PMID] 31082799.
2019
Plasma Fibroblast Growth Factor 21 Is Associated With Severity of Nonalcoholic Steatohepatitis in Patients With Obesity and Type 2 Diabetes.
The Journal of clinical endocrinology and metabolism. 104(8):3327-3336 [DOI] 10.1210/jc.2018-02414. [PMID] 30848827.
2019
Role of Vitamin E for Nonalcoholic Steatohepatitis in Patients With Type 2 Diabetes: A Randomized Controlled Trial.
Diabetes care. 42(8):1481-1488 [DOI] 10.2337/dc19-0167. [PMID] 31332029.
2019
Use of Plasma Fragments of Propeptides of Type III, V, and VI Procollagen for the Detection of Liver Fibrosis in Type 2 Diabetes.
Diabetes care. 42(7):1348-1351 [DOI] 10.2337/dc18-2578. [PMID] 31221701.
2018
Clinical and Histologic Characterization of Nonalcoholic Steatohepatitis in African American Patients.
Diabetes care. 41(1):187-192 [DOI] 10.2337/dc17-1349. [PMID] 29133343.
2018
Pioglitazone improves hepatic mitochondrial function in a mouse model of nonalcoholic steatohepatitis.
American journal of physiology. Endocrinology and metabolism. 315(2):E163-E173 [DOI] 10.1152/ajpendo.00023.2018. [PMID] 29634314.
2018
Response to Pioglitazone in Patients With Nonalcoholic Steatohepatitis With vs Without Type 2 Diabetes.
Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association. 16(4):558-566.e2 [DOI] 10.1016/j.cgh.2017.12.001. [PMID] 29223443.
2018
Use of a metabolomic approach to non-invasively diagnose non-alcoholic fatty liver disease in patients with type 2 diabetes mellitus.
Diabetes, obesity & metabolism. 20(7):1702-1709 [DOI] 10.1111/dom.13285. [PMID] 29527789.
2017
Concentration-dependent response to pioglitazone in nonalcoholic steatohepatitis.
Alimentary pharmacology & therapeutics. 46(1):56-61 [DOI] 10.1111/apt.14111. [PMID] 28470881.
2017
Corrigendum: Mitochondrial ATP transporter depletion protects mice against liver steatosis and insulin resistance.
Nature communications. 8 [DOI] 10.1038/ncomms16143. [PMID] 31305776.
2017
Improved experimental data processing for UHPLC–HRMS/MS lipidomics applied to nonalcoholic fatty liver disease
Metabolomics. [DOI] 10.1007/s11306-017-1280-1.
2017
Mitochondrial ATP transporter depletion protects mice against liver steatosis and insulin resistance.
Nature communications. 8 [DOI] 10.1038/ncomms14477. [PMID] 28205519.
2016
Lipotoxicity in steatohepatitis occurs despite an increase in tricarboxylic acid cycle activity.
American journal of physiology. Endocrinology and metabolism. 310(7):E484-94 [DOI] 10.1152/ajpendo.00492.2015. [PMID] 26814015.
2016
Plasma thyroid hormone concentration is associated with hepatic triglyceride content in patients with type 2 diabetes.
Journal of investigative medicine : the official publication of the American Federation for Clinical Research. 64(1):63-8 [DOI] 10.1136/jim-2015-000019. [PMID] 26755815.
2015
Cross-talk between branched-chain amino acids and hepatic mitochondria is compromised in nonalcoholic fatty liver disease.
American journal of physiology. Endocrinology and metabolism. 309(4):E311-9 [DOI] 10.1152/ajpendo.00161.2015. [PMID] 26058864.
2015
Genomic Landscape of Primary Mediastinal B-Cell Lymphoma Cell Lines.
PloS one. 10(11) [DOI] 10.1371/journal.pone.0139663. [PMID] 26599546.

Grants

Dec 2023 ACTIVE
A Phase 3, randomised, double-blind, parallel-group, 76-week, efficacy and safety study of BI 456906 administered subcutaneously compared with placebo in participants with overweight or obesity and type 2 diabetes mellitus
Role: Other
Funding: BOEHRINGER INGELHEIM PHARM INC

Contact Details

Phones:
Business:
(352) 273-8490
Addresses:
Business Mailing:
PO Box 100226
GAINESVILLE FL 32610
Business Street:
1600 SW ARCHER RD
GAINESVILLE FL 32610