Naykky Singh Ospina

Naykky Singh Ospina, MD

Clinical Associate Professor

Department: MD-ENDOCRINOLOGY
Business Phone: (352) 273-8655

About Naykky Singh Ospina

Dr. Singh Ospina is an Associate Professor in the Division of Endocrinology, Diabetes and Metabolism at the University of Florida. She is board certified in Internal Medicine. She was awarded her medical degree from the University of Panama, Panama. She completed her Internal Medicine residency at the John H. Stroger, Jr. Hospital of Cook County.  She received her Endocrinology, Diabetes and Metabolism fellowship training at the Mayo Clinic, Rochester where she also completed a Master in Clinical and Translational Science.

Board Certifications

  • Internal Medicine
    American Board of Internal Medicine

Clinical Profile

Specialties
  • Endocrinology, Diabetes and Metabolism
  • Endocrinology, Diabetes and Metabolism
Areas of Interest
  • Primary hyperparathyroidism
  • Thyroid nodule

Research Profile

Open Researcher and Contributor ID (ORCID)

0000-0001-7229-5061

Publications

2024
Appropriateness of Levothyroxine Prescription: A Multicenter Retrospective Study.
The Journal of clinical endocrinology and metabolism. 109(2):e765-e772 [DOI] 10.1210/clinem/dgad517. [PMID] 37656124.
2024
Clinician feedback using a shared decision-making tool for the evaluation of patients with thyroid nodules-an observational study.
Endocrine. 83(2):449-458 [DOI] 10.1007/s12020-023-03519-z. [PMID] 37695453.
2024
Defining inappropriate thyroid biopsy?-Proposed definition based on clinical evidence and stakeholder engagement.
Endocrine. [DOI] 10.1007/s12020-024-03727-1. [PMID] 38407695.
2024
Glucagon-Like Peptide-1 Receptor Agonists and Thyroid Cancer: A Narrative Review.
Thyroid : official journal of the American Thyroid Association. 34(4):403-418 [DOI] 10.1089/thy.2023.0530. [PMID] 38343381.
2024
Physical Examination of the Thyroid: Accuracy in Detecting Thyroid Nodules and Frequency of Additional Findings.
Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists. 30(1):31-35 [DOI] 10.1016/j.eprac.2023.10.002. [PMID] 37805101.
2024
Social Determinants of Health and Disparities in Thyroid Care.
The Journal of clinical endocrinology and metabolism. 109(3):e1309-e1313 [DOI] 10.1210/clinem/dgad716. [PMID] 38057150.
2024
Some patients with type 2 diabetes may benefit from intensive glycaemic and blood pressure control: A post-hoc machine learning analysis of ACCORD trial data.
Diabetes, obesity & metabolism. 26(4):1502-1509 [DOI] 10.1111/dom.15453. [PMID] 38297986.
2024
Trends and Components of Thyroid Status Evaluation in Commercially Insured Adults in the United States, 2006-2020.
The Journal of clinical endocrinology and metabolism. 109(3):611-618 [DOI] 10.1210/clinem/dgad632. [PMID] 37889845.
2023
Artificial Intelligence in Thyroidology: A Narrative Review of the Current Applications, Associated Challenges, and Future Directions.
Thyroid : official journal of the American Thyroid Association. 33(8):903-917 [DOI] 10.1089/thy.2023.0132. [PMID] 37279303.
2023
Collaborative Diagnostic Conversations Between Clinicians, Patients, and Their Families: A Way to Avoid Diagnostic Errors.
Mayo Clinic proceedings. Innovations, quality & outcomes. 7(4):291-300 [DOI] 10.1016/j.mayocpiqo.2023.06.001. [PMID] 37457857.
2023
Concomitant use of levothyroxine and interacting medications in U.S. ambulatory care visits.
Journal of the American Pharmacists Association : JAPhA. 63(5):1553-1557.e3 [DOI] 10.1016/j.japh.2023.06.008. [PMID] 37329957.
2023
Determinants for Thyroid Hormone Replacement Therapy in Subclinical Hypothyroidism: A Multicenter Electronic Health Records-Based Study.
Thyroid : official journal of the American Thyroid Association. 33(9):1045-1054 [DOI] 10.1089/thy.2023.0062. [PMID] 37279296.
2023
Does the duration of ambulatory consultations affect the quality of healthcare? A systematic review.
BMJ open quality. 12(4) [DOI] 10.1136/bmjoq-2023-002311. [PMID] 37875307.
2023
Drivers of Thyroid Ultrasound Use: A Retrospective Observational Study.
Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists. 29(12):948-954 [DOI] 10.1016/j.eprac.2023.09.006. [PMID] 37722595.
2023
Implementation strategies to support ultrasound thyroid nodule risk stratification: A systematic review.
Clinical endocrinology. 99(4):417-427 [DOI] 10.1111/cen.14942. [PMID] 37393196.
2023
Novel assessment of epigenetic imprinting biomarkers for the diagnosis of thyroid nodules.
Nature reviews. Clinical oncology. 20(3):139-140 [DOI] 10.1038/s41571-022-00720-3. [PMID] 36646815.
2023
Overuse of thyroid ultrasound.
Current opinion in endocrinology, diabetes, and obesity. 30(5):225-230 [DOI] 10.1097/MED.0000000000000814. [PMID] 37288725.
2023
Patient feedback receiving care using a shared decision making tool for thyroid nodule evaluation-an observational study.
Endocrine. 80(1):124-133 [DOI] 10.1007/s12020-022-03277-4. [PMID] 36534326.
2023
Thyroid Cancer Risk Communication in Patients with Thyroid Nodules.
Journal of cancer education : the official journal of the American Association for Cancer Education. 38(4):1234-1240 [DOI] 10.1007/s13187-022-02253-w. [PMID] 36602695.
2022
A Survey on the Management of Thyroid Eye Disease Among American and European Thyroid Association Members.
Thyroid : official journal of the American Thyroid Association. 32(12):1535-1546 [DOI] 10.1089/thy.2022.0172. [PMID] 35946071.
2022
Association between maternal thyroid function and risk of gestational hypertension and pre-eclampsia: a systematic review and individual-participant data meta-analysis.
The lancet. Diabetes & endocrinology. 10(4):243-252 [DOI] 10.1016/S2213-8587(22)00007-9. [PMID] 35255260.
2022
Clinician Agreement on the Classification of Thyroid Nodules Ultrasound Features: A Survey of 2 Endocrine Societies.
The Journal of clinical endocrinology and metabolism. 107(8):e3288-e3294 [DOI] 10.1210/clinem/dgac279. [PMID] 35521676.
2022
Development and pilot testing of a conversation aid to support the evaluation of patients with thyroid nodules.
Clinical endocrinology. 96(4):627-636 [DOI] 10.1111/cen.14599. [PMID] 34590734.
2022
Effect of Experiential Communication Skills Education on Graduate Medical Education Trainees’ Communication Behaviors: A Systematic Review.
Academic medicine : journal of the Association of American Medical Colleges. 97(12):1854-1866 [DOI] 10.1097/ACM.0000000000004883. [PMID] 35857395.
2022
Effect of metformin on microvascular outcomes in patients with type 2 diabetes: A systematic review and meta-analysis.
Diabetes research and clinical practice. 186 [DOI] 10.1016/j.diabres.2022.109821. [PMID] 35247521.
2021
ACR TI-RADS Recommendations: A Call to Contextualize Radiologists’ Recommendations for Thyroid Nodules With the Clinical Scenario.
Journal of the American College of Radiology : JACR. 18(9):1342-1344 [DOI] 10.1016/j.jacr.2021.04.019. [PMID] 34043976.
2021
Are American follow-up recommendations in endocrinology actionable? A systematic review of clinical practice guidelines.
Endocrine. 72(2):375-384 [DOI] 10.1007/s12020-020-02592-y. [PMID] 33475975.
2021
Benefits and Harms of Levothyroxine/L-Triiodothyronine Versus Levothyroxine Monotherapy for Adult Patients with Hypothyroidism: Systematic Review and Meta-Analysis.
Thyroid : official journal of the American Thyroid Association. 31(11):1613-1625 [DOI] 10.1089/thy.2021.0270. [PMID] 34340589.
2021
Clinical Outcomes After Discontinuation of Thyroid Hormone Replacement: A Systematic Review and Meta-Analysis.
Thyroid : official journal of the American Thyroid Association. 31(5):740-751 [DOI] 10.1089/thy.2020.0679. [PMID] 33161885.
2021
Inappropriate use of thyroid ultrasound: a systematic review and meta-analysis.
Endocrine. 74(2):263-269 [DOI] 10.1007/s12020-021-02820-z. [PMID] 34379311.
2021
Knowledge, Attitudes, Beliefs, and Treatment Burden Related to the Use of Levothyroxine in Hypothyroid Pregnant Women in the United States.
Thyroid : official journal of the American Thyroid Association. 31(4):669-677 [DOI] 10.1089/thy.2020.0629. [PMID] 33176609.
2021
Sexual Harassment Experiences Across the Academic Medicine Hierarchy.
Cureus. 13(2) [DOI] 10.7759/cureus.13508. [PMID] 33786217.
2021
Ultrasound Image Classification of Thyroid Nodules Using Machine Learning Techniques.
Medicina (Kaunas, Lithuania). 57(6) [DOI] 10.3390/medicina57060527. [PMID] 34074037.
2020
Educational programs to teach shared decision making to medical trainees: A systematic review.
Patient education and counseling. 103(6):1082-1094 [DOI] 10.1016/j.pec.2019.12.016. [PMID] 32005556.
2020
Management of Hypothyroidism in Patients with Acute Myocardial Infarction.
Medicina (Kaunas, Lithuania). 56(5) [DOI] 10.3390/medicina56050214. [PMID] 32353935.
2020
Patient Experiences and Perceptions Associated with the Use of Desiccated Thyroid Extract.
Medicina (Kaunas, Lithuania). 56(4) [DOI] 10.3390/medicina56040161. [PMID] 32260044.
2020
Patterns of Use, Efficacy, and Safety of Treatment Options for Patients with Graves’ Disease: A Nationwide Population-Based Study.
Thyroid : official journal of the American Thyroid Association. 30(3):357-364 [DOI] 10.1089/thy.2019.0132. [PMID] 31973681.
2020
The Mismatch of Nutrition and Lifestyle Beliefs and Actions Among Physicians: A Wake-Up Call.
American journal of lifestyle medicine. 14(3):304-315 [DOI] 10.1177/1559827619883603. [PMID] 32477033.
2020
Thyroid nodules: diagnostic evaluation based on thyroid cancer risk assessment.
BMJ (Clinical research ed.). 368 [DOI] 10.1136/bmj.l6670. [PMID] 31911452.
2019
Assessment of The Bethesda System for Reporting Thyroid Cytopathology.
American journal of clinical pathology. 152(4):502-511 [DOI] 10.1093/ajcp/aqz076. [PMID] 31305880.
2019
Eliciting the Patient’s Agenda- Secondary Analysis of Recorded Clinical Encounters.
Journal of general internal medicine. 34(1):36-40 [DOI] 10.1007/s11606-018-4540-5. [PMID] 29968051.
2019
Impact of decision aids used during clinical encounters on clinician outcomes and consultation length: a systematic review.
BMJ quality & safety. 28(6):499-510 [DOI] 10.1136/bmjqs-2018-008022. [PMID] 30301874.
2019
Physicians Interrupting Patients.
Journal of general internal medicine. 34(10) [DOI] 10.1007/s11606-019-05141-0. [PMID] 31289991.
2019
Practice Variation in the Care of Subclinical Hypothyroidism During Pregnancy: A National Survey of Physicians in the United States.
Journal of the Endocrine Society. 3(10):1892-1906 [DOI] 10.1210/js.2019-00196. [PMID] 31598570.
2019
Reflecting on shared decision making: A reflection-quantification study.
Health expectations : an international journal of public participation in health care and health policy. 22(5):1165-1172 [DOI] 10.1111/hex.12953. [PMID] 31414553.
2019
Thyroid hormones treatment for subclinical hypothyroidism: a clinical practice guideline.
BMJ (Clinical research ed.). 365 [DOI] 10.1136/bmj.l2006. [PMID] 31088853.
2019
Variation in Treatment Practices for Subclinical Hypothyroidism in Pregnancy: US National Assessment.
The Journal of clinical endocrinology and metabolism. 104(9):3893-3901 [DOI] 10.1210/jc.2019-00057. [PMID] 31127823.
2018
Commentary: Effect of Levothyroxine on Miscarriage among Women with Normal Thyroid Function and Thyroid Autoimmunity Undergoing In Vitro Fertilization and Embryo Transfer: A Randomized Clinical Trial.
Frontiers in endocrinology. 9 [DOI] 10.3389/fendo.2018.00073. [PMID] 29569649.
2018
Humor During Clinical Practice: Analysis of Recorded Clinical Encounters.
Journal of the American Board of Family Medicine : JABFM. 31(2):270-278 [DOI] 10.3122/jabfm.2018.02.170313. [PMID] 29535244.
2018
Patients’ knowledge about the outcomes of thyroid biopsy: a patient survey.
Endocrine. 61(3):482-488 [DOI] 10.1007/s12020-018-1639-8. [PMID] 29909600.
2018
Subclinical Hypothyroidism in Women Planning Conception and During Pregnancy: Who Should Be Treated and How?
Journal of the Endocrine Society. 2(6):533-546 [DOI] 10.1210/js.2018-00090. [PMID] 29850652.
2018
Weight Changes After Thyroid Surgery for Patients with Benign Thyroid Nodules and Thyroid Cancer: Population-Based Study and Systematic Review and Meta-Analysis.
Thyroid : official journal of the American Thyroid Association. 28(5):639-649 [DOI] 10.1089/thy.2017.0216. [PMID] 29631475.
2017
Assessing for Multiple Endocrine Neoplasia Type 1 in Patients Evaluated for Zollinger-Ellison Syndrome-Clues to a Safer Diagnostic Process.
The American journal of medicine. 130(5):603-605 [DOI] 10.1016/j.amjmed.2016.11.035. [PMID] 28011308.
2017
Sex Steroids and Cardiovascular Outcomes in Transgender Individuals: A Systematic Review and Meta-Analysis.
The Journal of clinical endocrinology and metabolism. 102(11):3914-3923 [DOI] 10.1210/jc.2017-01643. [PMID] 28945852.
2017
Systematic reviews of diagnostic tests in endocrinology: an audit of methods, reporting, and performance.
Endocrine. 57(1):18-34 [DOI] 10.1007/s12020-017-1298-1. [PMID] 28585154.
2017
Thyroid hormone treatment among pregnant women with subclinical hypothyroidism: US national assessment.
BMJ (Clinical research ed.). 356 [DOI] 10.1136/bmj.i6865. [PMID] 28122781.
2016
Antithyroid Drugs-The Most Common Treatment for Graves’ Disease in the United States: A Nationwide Population-Based Study.
Thyroid : official journal of the American Thyroid Association. 26(8):1144-5 [DOI] 10.1089/thy.2016.0222. [PMID] 27267495.
2016
Comparative efficacy of parathyroidectomy and active surveillance in patients with mild primary hyperparathyroidism: a systematic review and meta-analysis.
Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA. 27(12):3395-3407 [PMID] 27562567.
2016
Diagnostic accuracy of thyroid nodule growth to predict malignancy in thyroid nodules with benign cytology: systematic review and meta-analysis.
Clinical endocrinology. 85(1):122-31 [DOI] 10.1111/cen.12975. [PMID] 26562828.
2016
Diagnostic accuracy of ultrasound-guided fine needle aspiration biopsy for thyroid malignancy: systematic review and meta-analysis.
Endocrine. 53(3):651-61 [DOI] 10.1007/s12020-016-0921-x. [PMID] 27071659.
2016
Effects of Levothyroxine Therapy on Pregnancy Outcomes in Women with Subclinical Hypothyroidism.
Thyroid : official journal of the American Thyroid Association. 26(7):980-6 [DOI] 10.1089/thy.2016.0014. [PMID] 27112035.
2016
Outcomes of Parathyroidectomy in Patients with Primary Hyperparathyroidism: A Systematic Review and Meta-analysis.
World journal of surgery. 40(10):2359-77 [DOI] 10.1007/s00268-016-3514-1. [PMID] 27094563.
2016
Physical exam in asymptomatic people drivers the detection of thyroid nodules undergoing ultrasound guided fine needle aspiration biopsy.
Endocrine. 54(2):433-439 [PMID] 27510173.
2016
PREDICTORS OF BIOCHEMICAL REMISSION AND RECURRENCE AFTER SURGICAL AND RADIATION TREATMENTS OF CUSHING DISEASE: A SYSTEMATIC REVIEW AND META-ANALYSIS.
Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists. 22(4):466-75 [DOI] 10.4158/EP15922.RA. [PMID] 26789343.
2016
Prevalence of parathyroid carcinoma in 348 patients with multiple endocrine neoplasia type 1 – case report and review of the literature.
Clinical endocrinology. 84(2):244-249 [DOI] 10.1111/cen.12714. [PMID] 25557532.
2016
Prognosis of patients with benign thyroid nodules: a population-based study.
Endocrine. 54(1):148-155 [PMID] 27142412.
2016
Ramifications of New Terminology for Encapsulated Follicular Variant of Papillary Thyroid Carcinoma.
JAMA oncology. 2(8) [DOI] 10.1001/jamaoncol.2016.2208. [PMID] 27533607.
2016
When and how should patients with multiple endocrine neoplasia type 1 be screened for thymic and bronchial carcinoid tumours?
Clinical endocrinology. 84(1):13-6 [DOI] 10.1111/cen.12972. [PMID] 26562483.
2015
Is the endocrine research pipeline broken? A systematic evaluation of the Endocrine Society clinical practice guidelines and trial registration.
BMC medicine. 13 [DOI] 10.1186/s12916-015-0435-z. [PMID] 26265226.
2015
Safety and efficacy of percutaneous parathyroid ethanol ablation in patients with recurrent primary hyperparathyroidism and multiple endocrine neoplasia type 1.
The Journal of clinical endocrinology and metabolism. 100(1):E87-90 [DOI] 10.1210/jc.2014-3255. [PMID] 25337928.
2015
The Value of Repeat Thyroid Fine-Needle Aspiration Biopsy in Patients with a Previously Benign Result: How Often Does It Alter Management?
Thyroid : official journal of the American Thyroid Association. 25(10):1121-6 [DOI] 10.1089/thy.2015.0146. [PMID] 26177342.
2015
Thymic and Bronchial Carcinoid Tumors in Multiple Endocrine Neoplasia Type 1: The Mayo Clinic Experience from 1977 to 2013.
Hormones & cancer. 6(5-6):247-53 [DOI] 10.1007/s12672-015-0228-z. [PMID] 26070346.

Grants

Jul 2023 ACTIVE
De-implementation of inappropriate thyroid ultrasound
Role: Principal Investigator
Funding: MAYO CLINIC via NATL INST OF HLTH NCI
Dec 2022 ACTIVE
Assessing Barriers and Facilitators for Participating Structured Lifestyle Intervention
Role: Co-Investigator
Funding: EMORY UNIV via CTRS FOR DISEASE CONTROL AND PREVENTION
Sep 2022 – Dec 2022
Assessing Barriers and Facilitators for Participating Structured Lifestyle Intervention and Its Real-world Effectiveness and Cost-effectiveness among US Veterans
Role: Co-Investigator
Funding: CTRS FOR DISEASE CONTROL AND PREVENTION
Jul 2022 – Jun 2023
Developing a Framework for Understanding the Process of Diagnostic Reconciliation and Supporting Diagnostic Conversations
Role: Principal Investigator
Funding: NATIONAL ACADEMY OF MEDICINE via GORDON AND BETTY MOORE FOUNDATION
Jan 2022 ACTIVE
American Cancer Society Institutional Research Grant
Role: Project Manager
Funding: AMERICAN CANCER SOCIETY
Jul 2020 ACTIVE
Adequate selection of patients for thyroid biopsy: evaluation of a shared decision making conversation aid
Role: Principal Investigator
Funding: NATL INST OF HLTH NCI
Apr 2017 – Jun 2021
OoR CTSI Institutional Matching Support
Role: Project Manager
Funding: UF DIV OF SPONSORED RES MATCHING FUNDS

Education

Fellowship – Endocrinology, Diabetes, and Metabolism
2016 · Mayo Clinic
Residency – Internal Medicine
2013 · John Stroger Hospital
Medical Degree
2007 · Universidad de Panama

Contact Details

Phones:
Business:
(352) 273-8655
Addresses:
Business Mailing:
PO Box 100226
GAINESVILLE FL 32610